'Major setback' for the English camp after Atkinson leaves the field with a hamstring injury.
The English seamer further complicated England's injury problems after leaving the ground during Saturday's play of the fourth Ashes Test versus the Australians.
The right-arm seamer felt a problem in his left leg after the final ball of the fourth over during the morning session.
The touring camp stated the 27-year-old had experienced "tightness" and required time away from the action to undergo evaluation "over the next few hours".
The series decider in this Ashes battle at the SCG starts on Sunday, 4 January.
The English side has already lost key quicks Mark Wood with a knee problem and another paceman because of a side injury during this series.
Matthew Fisher was brought into the squad as cover for Wood.
The seamer had a tough time early in the series, managing only three wickets.
He was left out for the Adelaide match, before being recalled for the Boxing Day match in the playing XI.
Surrey's Atkinson showed better form in Melbourne, bagging two scalps during the host's first knock, then making 28 with the bat among just a trio of teammates to reach double figures.
Following a brief spell late on the first day, he returned for the second day's play and dismissed the nightwatchman edging to the keeper.
Yet, at the end of the fifth over, he delivered a change of pace to the batsman and suddenly grabbed at his leg.
Atkinson returned to the side for the Melbourne match after being left out the Adelaide game.
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